Estimate cost for an ADME prediction

POST/compute/v1/predictions/adme/estimate-cost

Estimate the cost of an ADME prediction without creating any resource or consuming GPU.

Body ParametersJSONExpand Collapse

input: object { molecules }

molecules: array of object { smiles, id }

Molecules to score (1-128 per request). Results are returned in the same order as this list.

smiles: string

SMILES string of the molecule to predict ADME properties for.

minLength1

id: optional string

Optional client-provided identifier. Returned as external_id in the matching output item.

minLength1

maxLength128

model: "adme-v1"

Model to use for prediction

idempotency_key: optional string

Client-provided key to prevent duplicate submissions on retries

maxLength255

workspace_id: optional string

Target workspace ID (admin keys only; ignored for workspace keys)

ReturnsExpand Collapse

breakdown: object { application, cost_per_unit_usd, num_units }

Cost breakdown for the billed application.

application: "structure_and_binding" or "small_molecule_design" or "small_molecule_library_screen" or 4 more

One of the following:

"structure_and_binding"

"small_molecule_design"

"small_molecule_library_screen"

"protein_design"

"protein_redesign"

"protein_library_screen"

"adme"

cost_per_unit_usd: string

Estimated cost per displayed unit as a decimal string, rounded up to 4 decimal places. This may include token-size multipliers or generation overhead; estimated_cost_usd is the authoritative total.

num_units: number

Number of billable units in the estimate. The unit depends on the endpoint: samples for structure-and-binding, molecules for ADME, and requested proteins or molecules for design/screen endpoints.

disclaimer: string

estimated_cost_usd: string

Estimated total cost as a decimal string

Estimate cost for an ADME prediction

curl https://api.boltz.bio/compute/v1/predictions/adme/estimate-cost \
    -H 'Content-Type: application/json' \
    -H "x-api-key: $BOLTZ_API_KEY" \
    -d '{
          "input": {
            "molecules": [
              {
                "smiles": "x"
              }
            ]
          },
          "model": "adme-v1"
        }'

{
  "breakdown": {
    "application": "structure_and_binding",
    "cost_per_unit_usd": "0.0500",
    "num_units": 1
  },
  "disclaimer": "This is an estimate only and may differ from your actual charges. Final billing is based on exact token counts computed at run time. For large library screens, the estimate is extrapolated from a sample and may be less accurate for highly variable inputs.",
  "estimated_cost_usd": "0.0500"
}

Returns Examples

{
  "breakdown": {
    "application": "structure_and_binding",
    "cost_per_unit_usd": "0.0500",
    "num_units": 1
  },
  "disclaimer": "This is an estimate only and may differ from your actual charges. Final billing is based on exact token counts computed at run time. For large library screens, the estimate is extrapolated from a sample and may be less accurate for highly variable inputs.",
  "estimated_cost_usd": "0.0500"
}