## Stop a running protein sequence redesign run

**post** `/compute/v1/protein/sequence-redesign/{id}/stop`

Stop an in-progress protein sequence redesign run early

### Path Parameters

- `id: string`

### Returns

- `id: string`

  Unique ProteinSequenceRedesignRun identifier

- `completed_at: string`

- `created_at: string`

- `data_deleted_at: string`

  When the input, output, and result data was permanently deleted. Null if data has not been deleted.

- `engine: "boltz-protein-redesign"`

  Deprecated. Use pipeline instead.

  - `"boltz-protein-redesign"`

- `engine_version: "v2026-07-14"`

  Deprecated. Use pipeline_version instead.

  - `"v2026-07-14"`

- `error: object { code, message, details }`

  - `code: string`

    Machine-readable error code

  - `message: string`

    Human-readable error message

  - `details: optional unknown`

    Additional field-level error details keyed by input path, when available.

- `input: object { entities, num_proteins, structure, 4 more }  or object { entities, num_proteins, structure, 4 more }`

  Pipeline input (null if data deleted)

  - `BinderProteinSequenceRedesignRunInputResponse object { entities, num_proteins, structure, 4 more }`

    - `entities: array of object { chain_id, role, type }  or object { chain_id, role, type, design_motifs }`

      Every chain in the input CIF, assigned exactly once as target or binder.

      - `BinderSequenceRedesignTargetEntityResponse object { chain_id, role, type }`

        A fixed target chain from the input CIF.

        - `chain_id: string`

        - `role: "target"`

          - `"target"`

        - `type: "from_template"`

          - `"from_template"`

      - `BinderSequenceRedesignBinderEntityResponse object { chain_id, role, type, design_motifs }`

        - `chain_id: string`

        - `role: "binder"`

          - `"binder"`

        - `type: "from_template"`

          - `"from_template"`

        - `design_motifs: optional array of object { filters, residues, type }`

          Residues to redesign. Omit this field to keep the binder chain fixed.

          - `filters: array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

            Filters applied to this motif in addition to global_design_filters.

            - `ExcludedAminoAcidsDesignFilterResponse object { amino_acids, type }`

              - `amino_acids: array of string`

                Single-letter amino-acid codes that must not occur in the filtered designed region.

              - `type: "excluded_amino_acids"`

                - `"excluded_amino_acids"`

            - `MaxHydrophobicFractionDesignFilterResponse object { max_fraction, type }`

              - `max_fraction: number`

              - `type: "max_hydrophobic_fraction"`

                - `"max_hydrophobic_fraction"`

            - `ExcludedSequenceMotifsDesignFilterResponse object { motifs, type }`

              - `motifs: array of string`

                Sequence motifs that must not occur. X matches any single residue.

              - `type: "excluded_sequence_motifs"`

                - `"excluded_sequence_motifs"`

          - `residues: array of number`

            0-indexed residues to redesign on this chain.

          - `type: "residues"`

            - `"residues"`

    - `num_proteins: number`

      Number of unique filter-passing redesigned proteins to generate.

    - `structure: object { url, url_expires_at }`

      - `url: string`

        URL to download the file

      - `url_expires_at: string`

        When the presigned URL expires

    - `type: "binder"`

      - `"binder"`

    - `global_design_filters: optional array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

      Filters applied to every redesigned region. When omitted, cysteine is excluded. Pass [] to disable global filters.

      - `ExcludedAminoAcidsDesignFilterResponse object { amino_acids, type }`

        - `amino_acids: array of string`

          Single-letter amino-acid codes that must not occur in the filtered designed region.

        - `type: "excluded_amino_acids"`

          - `"excluded_amino_acids"`

      - `MaxHydrophobicFractionDesignFilterResponse object { max_fraction, type }`

        - `max_fraction: number`

        - `type: "max_hydrophobic_fraction"`

          - `"max_hydrophobic_fraction"`

      - `ExcludedSequenceMotifsDesignFilterResponse object { motifs, type }`

        - `motifs: array of string`

          Sequence motifs that must not occur. X matches any single residue.

        - `type: "excluded_sequence_motifs"`

          - `"excluded_sequence_motifs"`

    - `idempotency_key: optional string`

    - `workspace_id: optional string`

      Workspace to run this redesign in.

  - `GenericProteinSequenceRedesignRunInputResponse object { entities, num_proteins, structure, 4 more }`

    - `entities: array of object { chain_id, type, design_motifs }`

      Every chain in the input CIF, assigned exactly once.

      - `chain_id: string`

      - `type: "from_template"`

        - `"from_template"`

      - `design_motifs: optional array of object { filters, residues, type }`

        Residues to redesign. Omit this field to keep the chain fixed.

        - `filters: array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

          Filters applied to this motif in addition to global_design_filters.

          - `ExcludedAminoAcidsDesignFilterResponse object { amino_acids, type }`

            - `amino_acids: array of string`

              Single-letter amino-acid codes that must not occur in the filtered designed region.

            - `type: "excluded_amino_acids"`

              - `"excluded_amino_acids"`

          - `MaxHydrophobicFractionDesignFilterResponse object { max_fraction, type }`

            - `max_fraction: number`

            - `type: "max_hydrophobic_fraction"`

              - `"max_hydrophobic_fraction"`

          - `ExcludedSequenceMotifsDesignFilterResponse object { motifs, type }`

            - `motifs: array of string`

              Sequence motifs that must not occur. X matches any single residue.

            - `type: "excluded_sequence_motifs"`

              - `"excluded_sequence_motifs"`

        - `residues: array of number`

          0-indexed residues to redesign on this chain.

        - `type: "residues"`

          - `"residues"`

    - `num_proteins: number`

      Number of unique filter-passing redesigned proteins to generate.

    - `structure: object { url, url_expires_at }`

      - `url: string`

        URL to download the file

      - `url_expires_at: string`

        When the presigned URL expires

    - `type: "generic"`

      - `"generic"`

    - `global_design_filters: optional array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

      Filters applied to every redesigned region. When omitted, cysteine is excluded. Pass [] to disable global filters.

      - `ExcludedAminoAcidsDesignFilterResponse object { amino_acids, type }`

        - `amino_acids: array of string`

          Single-letter amino-acid codes that must not occur in the filtered designed region.

        - `type: "excluded_amino_acids"`

          - `"excluded_amino_acids"`

      - `MaxHydrophobicFractionDesignFilterResponse object { max_fraction, type }`

        - `max_fraction: number`

        - `type: "max_hydrophobic_fraction"`

          - `"max_hydrophobic_fraction"`

      - `ExcludedSequenceMotifsDesignFilterResponse object { motifs, type }`

        - `motifs: array of string`

          Sequence motifs that must not occur. X matches any single residue.

        - `type: "excluded_sequence_motifs"`

          - `"excluded_sequence_motifs"`

    - `idempotency_key: optional string`

    - `workspace_id: optional string`

      Workspace to run this redesign in.

- `livemode: boolean`

  Whether this resource was created with a live API key.

- `pipeline: "boltz-protein-redesign"`

  - `"boltz-protein-redesign"`

- `pipeline_version: "v2026-07-14"`

  - `"v2026-07-14"`

- `progress: object { num_proteins_generated, total_proteins_to_generate, latest_result_id }`

  - `num_proteins_generated: number`

    Number of protein binders generated so far

  - `total_proteins_to_generate: number`

    Total number of protein binders requested

  - `latest_result_id: optional string`

    ID of the most recently generated result

- `started_at: string`

- `status: "pending" or "running" or "succeeded" or 2 more`

  - `"pending"`

  - `"running"`

  - `"succeeded"`

  - `"failed"`

  - `"stopped"`

- `stopped_at: string`

- `workspace_id: string`

  Workspace ID

- `idempotency_key: optional string`

  Client-provided idempotency key

### Example

```http
curl https://api.boltz.bio/compute/v1/protein/sequence-redesign/$ID/stop \
    -X POST \
    -H "x-api-key: $BOLTZ_API_KEY"
```

#### Response

```json
{
  "id": "id",
  "completed_at": "2019-12-27T18:11:19.117Z",
  "created_at": "2019-12-27T18:11:19.117Z",
  "data_deleted_at": "2019-12-27T18:11:19.117Z",
  "engine": "boltz-protein-redesign",
  "engine_version": "v2026-07-14",
  "error": {
    "code": "code",
    "message": "message",
    "details": {}
  },
  "input": {
    "entities": [
      {
        "chain_id": "x",
        "role": "target",
        "type": "from_template"
      },
      {
        "chain_id": "x",
        "role": "target",
        "type": "from_template"
      }
    ],
    "num_proteins": 1,
    "structure": {
      "url": "https://example.com",
      "url_expires_at": "2019-12-27T18:11:19.117Z"
    },
    "type": "binder",
    "global_design_filters": [
      {
        "amino_acids": [
          "x"
        ],
        "type": "excluded_amino_acids"
      }
    ],
    "idempotency_key": "idempotency_key",
    "workspace_id": "workspace_id"
  },
  "livemode": true,
  "pipeline": "boltz-protein-redesign",
  "pipeline_version": "v2026-07-14",
  "progress": {
    "num_proteins_generated": 0,
    "total_proteins_to_generate": 1,
    "latest_result_id": "latest_result_id"
  },
  "started_at": "2019-12-27T18:11:19.117Z",
  "status": "pending",
  "stopped_at": "2019-12-27T18:11:19.117Z",
  "workspace_id": "workspace_id",
  "idempotency_key": "idempotency_key"
}
```