## Resume a stopped protein sequence redesign run

`$ boltz-api protein:sequence-redesign resume`

**post** `/compute/v1/protein/sequence-redesign/{id}/resume`

Resume a stopped protein sequence redesign run from its last checkpoint

### Parameters

- `--id: string`

  Sequence redesign run ID

### Returns

- `ProteinSequenceRedesignResumeResponse: object { id, completed_at, created_at, 14 more }`

  A fixed-structure protein sequence redesign run.

  - `id: string`

    Unique ProteinSequenceRedesignRun identifier

  - `completed_at: string`

  - `created_at: string`

  - `data_deleted_at: string`

    When the input, output, and result data was permanently deleted. Null if data has not been deleted.

  - `engine: "boltz-protein-redesign"`

    Deprecated. Use pipeline instead.

  - `engine_version: "v2026-07-14"`

    Deprecated. Use pipeline_version instead.

  - `error: object { code, message, details }`

    - `code: string`

      Machine-readable error code

    - `message: string`

      Human-readable error message

    - `details: optional unknown`

      Additional field-level error details keyed by input path, when available.

  - `input: object { entities, num_proteins, structure, 4 more }  or object { entities, num_proteins, structure, 4 more }`

    Pipeline input (null if data deleted)

    - `BinderProteinSequenceRedesignRunInputResponse: object { entities, num_proteins, structure, 4 more }`

      - `entities: array of object { chain_id, role, type }  or object { chain_id, role, type, design_motifs }`

        Every chain in the input CIF, assigned exactly once as target or binder.

        - `BinderSequenceRedesignTargetEntityResponse: object { chain_id, role, type }`

          A fixed target chain from the input CIF.

          - `chain_id: string`

          - `role: "target"`

          - `type: "from_template"`

        - `BinderSequenceRedesignBinderEntityResponse: object { chain_id, role, type, design_motifs }`

          - `chain_id: string`

          - `role: "binder"`

          - `type: "from_template"`

          - `design_motifs: optional array of object { filters, residues, type }`

            Residues to redesign. Omit this field to keep the binder chain fixed.

            - `filters: array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

              Filters applied to this motif in addition to global_design_filters.

              - `ExcludedAminoAcidsDesignFilterResponse: object { amino_acids, type }`

                - `amino_acids: array of string`

                  Single-letter amino-acid codes that must not occur in the filtered designed region.

                - `type: "excluded_amino_acids"`

              - `MaxHydrophobicFractionDesignFilterResponse: object { max_fraction, type }`

                - `max_fraction: number`

                - `type: "max_hydrophobic_fraction"`

              - `ExcludedSequenceMotifsDesignFilterResponse: object { motifs, type }`

                - `motifs: array of string`

                  Sequence motifs that must not occur. X matches any single residue.

                - `type: "excluded_sequence_motifs"`

            - `residues: array of number`

              0-indexed residues to redesign on this chain.

            - `type: "residues"`

      - `num_proteins: number`

        Number of unique filter-passing redesigned proteins to generate.

      - `structure: object { url, url_expires_at }`

        - `url: string`

          URL to download the file

        - `url_expires_at: string`

          When the presigned URL expires

      - `type: "binder"`

      - `global_design_filters: optional array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

        Filters applied to every redesigned region. When omitted, cysteine is excluded. Pass [] to disable global filters.

        - `ExcludedAminoAcidsDesignFilterResponse: object { amino_acids, type }`

          - `amino_acids: array of string`

            Single-letter amino-acid codes that must not occur in the filtered designed region.

          - `type: "excluded_amino_acids"`

        - `MaxHydrophobicFractionDesignFilterResponse: object { max_fraction, type }`

          - `max_fraction: number`

          - `type: "max_hydrophobic_fraction"`

        - `ExcludedSequenceMotifsDesignFilterResponse: object { motifs, type }`

          - `motifs: array of string`

            Sequence motifs that must not occur. X matches any single residue.

          - `type: "excluded_sequence_motifs"`

      - `idempotency_key: optional string`

      - `workspace_id: optional string`

        Workspace to run this redesign in.

    - `GenericProteinSequenceRedesignRunInputResponse: object { entities, num_proteins, structure, 4 more }`

      - `entities: array of object { chain_id, type, design_motifs }`

        Every chain in the input CIF, assigned exactly once.

        - `chain_id: string`

        - `type: "from_template"`

        - `design_motifs: optional array of object { filters, residues, type }`

          Residues to redesign. Omit this field to keep the chain fixed.

          - `filters: array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

            Filters applied to this motif in addition to global_design_filters.

            - `ExcludedAminoAcidsDesignFilterResponse: object { amino_acids, type }`

              - `amino_acids: array of string`

                Single-letter amino-acid codes that must not occur in the filtered designed region.

              - `type: "excluded_amino_acids"`

            - `MaxHydrophobicFractionDesignFilterResponse: object { max_fraction, type }`

              - `max_fraction: number`

              - `type: "max_hydrophobic_fraction"`

            - `ExcludedSequenceMotifsDesignFilterResponse: object { motifs, type }`

              - `motifs: array of string`

                Sequence motifs that must not occur. X matches any single residue.

              - `type: "excluded_sequence_motifs"`

          - `residues: array of number`

            0-indexed residues to redesign on this chain.

          - `type: "residues"`

      - `num_proteins: number`

        Number of unique filter-passing redesigned proteins to generate.

      - `structure: object { url, url_expires_at }`

        - `url: string`

          URL to download the file

        - `url_expires_at: string`

          When the presigned URL expires

      - `type: "generic"`

      - `global_design_filters: optional array of object { amino_acids, type }  or object { max_fraction, type }  or object { motifs, type }`

        Filters applied to every redesigned region. When omitted, cysteine is excluded. Pass [] to disable global filters.

        - `ExcludedAminoAcidsDesignFilterResponse: object { amino_acids, type }`

          - `amino_acids: array of string`

            Single-letter amino-acid codes that must not occur in the filtered designed region.

          - `type: "excluded_amino_acids"`

        - `MaxHydrophobicFractionDesignFilterResponse: object { max_fraction, type }`

          - `max_fraction: number`

          - `type: "max_hydrophobic_fraction"`

        - `ExcludedSequenceMotifsDesignFilterResponse: object { motifs, type }`

          - `motifs: array of string`

            Sequence motifs that must not occur. X matches any single residue.

          - `type: "excluded_sequence_motifs"`

      - `idempotency_key: optional string`

      - `workspace_id: optional string`

        Workspace to run this redesign in.

  - `livemode: boolean`

    Whether this resource was created with a live API key.

  - `pipeline: "boltz-protein-redesign"`

  - `pipeline_version: "v2026-07-14"`

  - `progress: object { num_proteins_generated, total_proteins_to_generate, latest_result_id }`

    - `num_proteins_generated: number`

      Number of protein binders generated so far

    - `total_proteins_to_generate: number`

      Total number of protein binders requested

    - `latest_result_id: optional string`

      ID of the most recently generated result

  - `started_at: string`

  - `status: "pending" or "running" or "succeeded" or 2 more`

    - `"pending"`

    - `"running"`

    - `"succeeded"`

    - `"failed"`

    - `"stopped"`

  - `stopped_at: string`

  - `workspace_id: string`

    Workspace ID

  - `idempotency_key: optional string`

    Client-provided idempotency key

### Example

```cli
boltz-api protein:sequence-redesign resume \
  --api-key 'My API Key' \
  --id id
```

#### Response

```json
{
  "id": "id",
  "completed_at": "2019-12-27T18:11:19.117Z",
  "created_at": "2019-12-27T18:11:19.117Z",
  "data_deleted_at": "2019-12-27T18:11:19.117Z",
  "engine": "boltz-protein-redesign",
  "engine_version": "v2026-07-14",
  "error": {
    "code": "code",
    "message": "message",
    "details": {}
  },
  "input": {
    "entities": [
      {
        "chain_id": "x",
        "role": "target",
        "type": "from_template"
      },
      {
        "chain_id": "x",
        "role": "target",
        "type": "from_template"
      }
    ],
    "num_proteins": 1,
    "structure": {
      "url": "https://example.com",
      "url_expires_at": "2019-12-27T18:11:19.117Z"
    },
    "type": "binder",
    "global_design_filters": [
      {
        "amino_acids": [
          "x"
        ],
        "type": "excluded_amino_acids"
      }
    ],
    "idempotency_key": "idempotency_key",
    "workspace_id": "workspace_id"
  },
  "livemode": true,
  "pipeline": "boltz-protein-redesign",
  "pipeline_version": "v2026-07-14",
  "progress": {
    "num_proteins_generated": 0,
    "total_proteins_to_generate": 1,
    "latest_result_id": "latest_result_id"
  },
  "started_at": "2019-12-27T18:11:19.117Z",
  "status": "pending",
  "stopped_at": "2019-12-27T18:11:19.117Z",
  "workspace_id": "workspace_id",
  "idempotency_key": "idempotency_key"
}
```